Additive manufacturing of medications and static light scattering analysis of mesoporous structures
Tikhomirov, Evgenii (2019)
Diplomityö
Tikhomirov, Evgenii
2019
School of Engineering Science, Laskennallinen tekniikka
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Julkaisun pysyvä osoite on
https://urn.fi/URN:NBN:fi-fe2019053017838
https://urn.fi/URN:NBN:fi-fe2019053017838
Tiivistelmä
The main focus of the project was on the development of a method for three-dimensional printing of matrixes of drug carriers. For implementation, a wide instruction was applied, because for the solution of problems it was required to create a device and software to automate and improve the characteristics of the printing process. In addition, it is worth noting the specificity of the materials used in the project - mesoporous nanostructures, which require pretreatment and loading of drugs. Different variations of the mesoporous matrix / solvent were used in the study, thereby achieving optimal printing conditions.As a result of the project, an analysis of geometric and morphological characteristics was carried out using SEM and EDS, the distribution of magnesium-containing mesoporous material Upsalite was estimated, the temporal dependence of the intensity of re-production of the samples was determined using the method of volume indicatrix of static light scattering.